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Emergency crews received a call just before 3.30am local time on Monday, and rescue efforts involving multiple agencies and personal watercraft were still underway as of 7.30am PST.
The US Coast Guard has been unable to board the boat and search for survivors because it keeps reigniting, Senior Chief Aaron Bemis said.
The walls of the sprawling nine-bedroom mansion are covered with images which offer a detailed look into the millionaire financier's illicit taste, specifically his fixation on young girls' derrieres.
Several of the photos featured Maxwell, who has been accused of recruiting victims on Epstein's behalf.
Ator's shooting spree, which began after a traffic stop, left seven dead, between the ages of 15 to 57.
Hurricane Dorian has brought 'extreme destruction' to the Bahamas with gusts of 225mph and up to 30 inches of rainfall.
Resurfaced videos show Palm Beach Police officers combing the now-infamous .4million property where Epstein and his high-profile associates allegedly sexually abused many underage girls.
The vessel reportedly caught fire near Platts Harbor on Santa Cruz Island in the middle of the night while passengers were sleeping.
Five people have been rescued and 34 people are currently missing, according to Santa Barbara County Fire Department PIO Mark Eliason.